Scientific breakthroughs and basic research are frequently published in prestigious journals and praised for their impact. However, progress in clinical medicine is tedious and slow. There is still a distinct and even widening gap between basic science and clinical application. The dialog between basic science and clinical research has therefore to be intensified and a new culture of cooperation between basic and physician-scientists will become necessary to accelerate the transfer of new drugs into clinical practice.
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H. Graeff (1998) studied this question.
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