Dendritic cells have the option to express IDO-mediated suppression or not

In their recent article,[1][1] Terness et al contrast their findings with ours (D.H.M. and A.L.M.) regarding indoleamine 2,3-dioxygenase (IDO)–mediated suppression by certain human monocyte–derived dendritic cells (DCs) in vitro.[2][2],[3][3] We used this model to make the point that there can