Why the study?
The direction and strength of the association of shared cardiovascular risk factors with disease onset, subsequent disease incidence, and mortality in MI and AF were not completely understood.
Population
108 363 individuals free of MI and AF at baseline from 6 European population-based cohorts
Comparison
Risk factors and temporal relations for incident MI vs AF vs both
Design
Pooled cohort study using multivariable Cox regression analyses
Follow-up
Maximum follow-up of 10.0 years
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Patients with AF or MI warrant monitoring for the alternate condition; extends bidirectional mortality links but remains hypothesis-generating in observational data.
Cardiovascular risk factors show distinct associations with incident MI and AF, and the subsequent development of one condition after the other significantly increases mortality risk.
A 2022 study studied this question.