Combination chemotherapy may occasionally cause pneumothorax in patients with pulmonary metastases.
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May warrant vigilance for pneumothorax during chemotherapy with pulmonary metastases; hypothesis-generating case report leaves causality open.
Two patients with pulmonary metastases from synovial sarcoma and germ-cell tumor developed first bilateral, then repeated unilateral pneumothoraces during combination chemotherapy. It is suggested that chemotherapy may occasionally cause pneumothorax.
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Lote et al. (1981) studied this question.
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