Why the study?
Does proximal disarticulation provide therapeutic value in terms of recurrence, survival, and quality of life in patients with soft tissue and bone sarcomas?
Does proximal disarticulation provide therapeutic value in terms of recurrence, survival, and quality of life in patients with soft tissue and bone sarcomas?
Proximal disarticulation for soft tissue and bone sarcomas yields acceptable survival and excellent quality of life, regardless of prior radio- or chemotherapy.
May support proximal disarticulation for sarcomas with acceptable outcomes; leaves open need for controlled trials before practice change.
The authors have reviewed 23 patients with proximal disarticulations with the aim of assessing the therapeutic value in sarcoma, taking into account previous radio‐ and chemotherapy. The following criteria were especially examined: recurrences, survival, and quality of life. There were 14 soft tissue sarcomas, and 9 bone sarcomas. In 11 cases, the tumor was primary and treated for the first time while, in 12 cases, it was recurrent. Eighteen patients had been previously treated by nonradical surgery, 11 by radiotherapy, and 10 by chemotherapy. For upper limb tumors, 6 patients underwent an interscapulothoracic disarticulation, and 3 an interscapulothoracic resection according to Tikhoff‐Linberg. For lower limb tumors, 8 patients were submitted to interilioabdominal disarticulation, 3 to coxofemoral disarticulation, and 1 to internal hemipelvectomy according to Eilber. The mean disease‐free interval has been 34 months, and the mean survival, 38.5 months. Three (15%) of 20 evaluable patients recurred locally, although most of them benefited from second surgery. Quality of life has been excellent, in general, despite the fact that only 8 patients accepted to wear a prosthesis. The Karnofsky index ranged from 60 to 100%. No significant difference was seen, whether or not previous radio‐ and/or chemotherapy had been administered .
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Liénard et al. (1988) studied this question.
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