Psilocin analogs II. Synthesis of 3‐[2‐(dialkylamino)ethyl]‐, 3‐[2‐(N‐methyl‐N‐alkylamino)ethyl]‐, and 3‐[2‐(cycloalkylamino)ethyl]indol‐4‐ols

Structural alteration of the N b ‐substituents of psilocin (3‐[2‐dimethylamino)ethyl]indol‐4‐ol) ( 12a ) has led to a number of compounds containing known pharmacophoric groups. Further, it is hoped that the subtle changes in the nature of these substituents may lead to a clearer understanding of the structure‐activity relationships of the 4‐hydroxytryptamine hallucinogens.