A simpler label. Various redox and optical markers have been easily loaded in the cavity of apoferritin to develop novel and versatile nanoparticle labels for optical and electrochemical bioassays. Such use of apoferritin nanovehicles offers convenient loading and releasing of the markers of interest by pH control instead of harsher conditions and avoids complicated nanoparticle syntheses. The new nanoparticle labels could be applicable to other biological assays, particularly immunoassays.
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Liu et al. (2006) studied this question.
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