CommentSystolic blood pressure was not indicative of blood cyanide levels and oxyhaemoglobin saturation gradient did not parallel decreases in blood cyanide concen- trations.Concentration decay curves suggest that plasma lactate concentration is closely related to blood cyanide concentration before and after hydroxoco- balamin treatment.If this is confirmed in other cases of pure cyanide intoxication serial plasma lactate concen- trations could be used as a marker of the evolution of cyanide toxicity and perhaps of the adequacy of treatment.
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Mortier et al. (1996) studied this question.
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