Lymph Vessels in Rabbit Carcinoma

In 1908, Evans¹published a short article on the occurrence of newly formed lymphatic vessels in malignant growths. In this paper he stated that important publications and books of reference, such as those of Borst,²Ribbert, Ziegler, Lubarsch-Ostertag and Thoma, failed to report "any instance in which proper lymphatic vessels were found growing in malignant tissue." In fact, that statement holds good today, because examination of more recently published volumes, such as the exhaustive work of Ewing³on neoplastic diseases, and of the textbooks of Aschoff,⁴Karsner,⁵Sternberg⁶and Adami,⁷has showed that they have nothing to add to the previous works on this subject. The textbook of MacCallum,⁸however, is an exception, because here it is stated that as a result of the injection experiments of Evans, it is known that lymphatics are abundantly present in human tumors. This work of