Why the study?
Reported pregnancies in women with repaired truncus arteriosus are rare, but improved surgical techniques allow more women with conotruncal defects to reach reproductive age.
This case report highlights the use of sonography for prenatal diagnosis of concordant congenital heart disease in the offspring of a mother with repaired truncus arteriosus.
Supports targeted prenatal sonography in repaired truncus arteriosus; leaves open recurrence risk quantification.
Reported pregnancies in women with repaired truncus arteriosus are rare. As a result of improved surgical techniques, more women with conotruncal defects are now reaching reproductive age. Multifactorial inheritance rather than single gene mutation is the causative agent of most congenital heart disease. The environment can play an important and varied role in direct transmission, particularly in incidences where genes predispose a defect. This may be one of the first reported cases discussing a pregnant mother with repaired truncus arteriosus and her fetus, prenatally diagnosed with a concordant truncal defect.
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Fyock et al. (2019) studied this question.
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