Bicontinuous, thermosensitive, L3-phase silica nanocomposites are prepared by self-assembly of silicified L3-phase silicates and L3-phase silicates integrated with thermoresponsive poly(N-isopropylacryl amide) (PNIPAm; see Figure). In the L3-PNIPAm material, interpenetrating nanoscale networks of silica and polymer gel are formed, with which highly controlled drug delivery is successfully demonstrated.
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Chang et al. (2005) studied this question.
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