The objective of the article by Becker et al.1 was “to explore the association between antihypertensive drug use and the risk of developing a first-time diagnosis of Parkinson’s disease (PD).” However, the authors mention the possible neuroprotective effects of angiotensin converting enzyme inhibitors and calcium channel blockers. If addressing possible neuroprotective effects is the primary purpose of the investigation, the logical analysis would be to examine whether use of different classes of antihypertensives among individuals …
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Ascherio et al. (2009) studied this question.
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