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January 1, 1978The Journal of AntibioticsOpen Access

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. I. Isolation and characterization of a pentose-excreting auxotrophic mutant of Nocardia mediterranei with drastically reduced rifamycin production.

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OGOreste GhisalbaNovartis (Switzerland)JNJ. NüeschNovartis (Switzerland)

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Ghisalba et al. (1978) studied this question.

synapsesocial.com/papers/6a83fbaca91c8d236ee668c3https://doi.org/10.7164/antibiotics.31.202
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  1. 1Ansamycin Biogenesis: Studies on a Novel Rifamycin Isolated from a Mutant Strain of Nocardia mediterranei1974 · 54 citations