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January 1, 2011Heart AsiaOpen Access

The 1-year combined endpoint of CV death, MI, or stroke was 4.38% (95% CI 4.20 to 4.56) in non-Asian regions, 4.65% (95% CI 4.04 to 5.25) in Asia excluding Japan, and 3.40% (95% CI 2.76 to 4.04, p<0.05) in Japan.

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Population

68,236 stable outpatients with established atherothrombosis or ≥3 atherothrombotic risk factors from 44…

Design

Cohort

Follow-up

1 year

Authors

SGShinya GotoYIY. IkedaJCJuliana C.N. Chan

Discussion

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Overview

Regional variations in CV outcomes may reflect ethnic factors; hypothesis-generating and requires prospective validation before guiding practice.

Structured PICO

P
Population
68,236 stable outpatients with established atherothrombosis or ≥3 atherothrombotic risk factors from 44 countries
O
Outcome
1-year cardiovascular (CV) outcomes (composite of CV death, myocardial infarction, stroke)composite

Asian patients with or at high risk of atherothrombosis have a higher prevalence of cerebrovascular disease and diabetes despite lower BMI, with 1-year cardiovascular event rates similar to non-Asian regions except for Japan, which has significantly lower rates.

Cite This Study

Goto et al. (2011) studied this question.

synapsesocial.com/papers/6a84034085a95bb87468bb11https://doi.org/10.1136/ha.2010.002691
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