Dendritic cobalamin ligands: The first dendritic ligands for vitamin B12 were identified from a combinatorial library of peptide dendrimers that feature metal-coordinating residues at the core. Molecular recognition and discrimination among different amino acid sequences revealed dendrimers with a polyanionic shell of glutamates and a coordinating cysteine or histidine at the core that displays favorable binding towards aquocobalamin.
No takes yet. Share an insight, caveat, or question.
Sommer et al. (2008) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: