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Intraluminal manometry and cineradiography have permitted the characterization of esophageal motor activity in various pathologic states, notably achalasia, diffuse spasm, hiatus hernia, reflux esophagitis, and collagen diseases. The results of such investigations have been compared with those obtained from young or middle-aged normal subjects, without consideration of the effect of aging alone.
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Soergel et al. (1964) studied this question.
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