Answers are grounded in this paper and cite their sources.
Photolysis of polyribobromouridylic acid with 313 nm light at neutral pH caused extensive debromination and a loss of A 280 (280–nm absorbance) without comparable increase in A 260 . At an exposure of 190μE/cm 2 , strand breakage occurred on the average of one break every 170 BrU residues. Little if any pyrimidine hydrate was produced. Exhaustive RNase hydrolysis of photolysed polymer gave a mixture of mononucleotides and oligonucleotides. The mononucleotide fraction was found to be composed of unaltered BrUMP and contained little if any UMP. Irradiation of the polymer at alkaline pH caused little or no debromination or spectral change.
No takes yet. Share an insight, caveat, or question.
Ehrlich et al. (1972) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: