A protecting‐group‐free two‐step approach for the preparation of tetrahydroquinolines has been developed. The procedure involves a highly regio‐ and enantioselective intermolecular iridium‐catalyzed allylic amination followed by one‐pot hydroboration and intramolecular Suzuki–Miyaura cross‐coupling. This method was applied in total syntheses of the alkaloids (+)‐angustureine and (–)‐cuspareine.
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Satyanarayana et al. (2011) studied this question.
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