Cloning and functional expression of a human eosinophil CC chemokine receptor.

Vol. 270, p. 16491 Page 16493, Figs. 3 and 4: The cells whose properties were described in these figures were not transfected with the CC CKR3 cDNA that we reported, but were inadvertently transfected instead with another CC chemokine receptor cDNA designated CC CKR5. Thus, the agonists for CC CKR5 are MIP-1α, MIP-1β, and RANTES (C. Combadiere, S. K. Ahuja, H. L. Tiffany, and P. M. Murphy, submitted for publication). We have confirmed the DNA and deduced protein sequences, genomic restriction fragments, and RNA distribution originally assigned to CC CKR3. When calcium mobilization was measured in transfected human embryonic kidney 293 cells, human eotaxin, an eosinophil-selective CC chemokine, was a potent agonist for CC CKR3, whereas MIP-1α, MIP-1β, and RANTES were inactive (M. Kitaura, T. Nakajima, T. Imai, S. Harada, C. Combadiere, H. L. Tiffany, P. M. Murphy, and O. Yoshie, submitted for publication). We regret the confusion caused by this error.