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(1) Nitration of 2-methylbenzothiazole gave 6-nitro-2-methylbenzothiazole, m. p. 165° (yield, 83%), along with a small amount of other mononitrobenzothiazole, m. p. 117° (yield, 3.7%). The product of m. p. 117° melted at 96-116° when mixed with 7-nitro-2-methylbenzothiazole, m. p. 120°.(2) Nitration of 2-methyl-6-acetylaminobenzothiazole gave 7-nitro-6-acetylamino-2-methylbenzothiazole in practically a qantitative yield. No other isomers, especially 5-nitro-6-acetylamino-2-methylbenzothiazole, were obtained.
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Mizuno et al. (1952) studied this question.
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