Treatment of Co-occurring Depression and Substance Dependence: Using Meta-analysis to Guide Clinical Recommendations

CME Educational Objectives 1) To understand how meta-analysis can be used to evaluate antidepressant treatment efficacy for depression in substance abusers seeking treatment. 2) To gain knowledge of what methodologic features of pharmacologic treatment trials targeting depressed substance abusers predict better treatment response. 3) To understand recommendations derived from findings of placebo-controlled antidepressant medication trials for clinical management and treatment of depressed, substance-dependent patients.