Radiofluoride Photoscanning of Bone for Reticulum Cell Sarcoma

Radiofluoride bone scanning is shown to be a sensitive means for detecting the bone lesions of reticulum cell sarcoma. This is in contrast to methods of bone photoscanning with radioisotopes of strontium which have failed to detect these lesions. Four patients with reticulum cell sarcoma involving bone were studied with¹⁸F bone scans. All four patients were scan positive for the bone lesions which were eventually demonstrated on roentgenograms or at postmortem examination. Concomitantly, x-ray studies of the bone were nondiagnostic in two of the patients. In one patient, a good clinical response to radiotherapy was correlated with a relative decrease in¹⁸F uptake in the treated area.