Why the study?
Does the level of epidural blockade (cervical vs lumbar) alter the cardiovascular stimulatory effects of intravenous ketamine?
Population
50 patients receiving either cervical epidural anesthesia, lumbar epidural anesthesia, or light general…
Comparison
Ketamine 2 mg/kg intravenously vs Comparison between cervical epidural anesthesia…
Design
Cohort
Follow-up
3-10 minutes following ketamine administration
Authors
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Cervical epidural was associated with blunted ketamine pressor effects; hypothesis-generating for sympathectomy modulation and requires prospective validation.
Does the level of epidural blockade (cervical vs lumbar) alter the cardiovascular stimulatory effects of intravenous ketamine?
High-level (cervical) epidural anesthesia partially suppresses the cardiovascular stimulatory effects of ketamine, likely due to cardiac sympathectomy.
Mayumi et al. (1985) studied this question.
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