Why the study?
Does radiofrequency catheter ablation of the slow pathway alter AV nodal electrophysiological characteristics over time in patients with AV nodal reentrant tachycardia?
Does radiofrequency catheter ablation of the slow pathway alter AV nodal electrophysiological characteristics over time in patients with AV nodal reentrant tachycardia?
Electrophysiological changes in the AV node immediately following slow pathway ablation for AVNRT are transient and recover by 3 months, likely due to changes in autonomic nervous tone.
Answers are grounded in this paper and cite their sources.
Transient post-ablation EP shifts require no practice change; leaves open autonomic mechanisms in AVNRT recovery.
Radiofrequency catheter ablation of the slow pathway is commonly used to treat atrioventricular (AV) nodal reentrant tachycardia. However, there has been little study of the follow-up assessment of AV nodal physiology. We compared AV nodal electrophysiological characteristics before, immediately after, and again 3 months after successful catheter ablation in 17 patients (mean age 50 +/- 16 years). Sinus cycle length, Wenckebach cycle length, A-H interval at a paced cycle length of 600 ms, effective refractory period and functional refractory period of the fast pathway were significantly changed immediately after catheter ablation, but had recovered 3 months after the procedure. There were no significant differences between the electrophysiological parameters immediately after catheter ablation and those 3 months after the procedure under the intravenous injection of atropine sulfate. We conclude that, due to changes in autonomic nervous tone, AV nodal electrophysiological characteristics are influenced immediately after catheter ablation of the slow pathway in AV nodal reentrant tachycardia.
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Enjoji et al. (1996) studied this question.
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