Key result
Ascending aortic diameter showed a strong positive correlation with left ventricular mass index (r = 0.745, p < 0.001) and a negative correlation with left ventricular ejection fraction.
Why the study?
Ascending aortic dilatation is a common clinical issue, prompting evaluation of the relationship between ascending aortic diameter with LV and LA functions and LVMI in individuals with normal LV systolic function.
Cross-Sectional (n=127)
Ascending aortic diameter correlates strongly with LV mass index and inversely with LV systolic and diastolic functions in healthy individuals with normal LV systolic function.
AIM: Ascending aortic dilatation is a common clinical issue. In the present study, we aimed to evaluate the relationship between ascending aortic diameter with left ventricular (LV) and left atrial (LA) functions, and LV mass index (LVMI) in a population with normal LV systolic function. METHODS: A total of 127 healthy participants with normal LV systolic function took part in the study. Echocardiographic measurements were obtained from each subject. RESULTS: The mean age of the participants was 43 ± 14.1 years and 76 (59.8%) were female. The mean aortic diameter of the participants was 32.2 ± 4.7 mm. A negative correlation was found between aortic diameter and LV systolic function (LVEF r = -.516, p < .001; Gls r = -.370). In addition, there was a strong positive correlation between aortic diameter with LV wall thicknesses, LVMI (r = .745, p < .001), and systolic and diastolic diameters. The relationship between aortic diameter and diastolic parameters was evaluated, a negative correlation with Mitral E, Em, E/A ratio, and a positive correlation with MPI, Mitral A, Am, E/Em ratio were found. CONCLUSION: A strong correlation between ascending aortic diameter with LV and LA functions, and LVMI in individuals with normal LV systolic function.
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Ergül et al. (2023) conducted a cross-sectional in Normal left ventricular systolic function (n=127). Ascending aortic diameter was evaluated on Correlation between ascending aortic diameter and left ventricular mass index (LVMI) (r = 0.745, p=<0.001). Ascending aortic diameter showed a strong positive correlation with left ventricular mass index (r = 0.745, p < 0.001) and a negative correlation with left ventricular ejection fraction.
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