Key result
South Asian stroke survivors had higher arterial stiffness and impaired endothelial function compared to European Caucasians (P<0.001), abnormalities independently associated with glycemic status.
Why the study?
Do South Asian stroke survivors have increased arterial stiffness and impaired endothelial function compared to European Caucasian stroke survivors?
Population
293 subjects including 100 South Asian stroke survivors, 60 European Caucasian stroke survivors, 60 SA with…
Comparison
South Asian ethnicity (observational exposure) vs European Caucasian ethnicity
Design
Cross-sectional
Authors
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Glycemic optimization may merit attention in South Asian stroke survivors; leaves open prospective validation of vascular and outcome links.
Cross-Sectional (n=293)
Do South Asian stroke survivors have increased arterial stiffness and impaired endothelial function compared to European Caucasian stroke survivors?
p-value: p=<0.001
South Asian stroke survivors exhibit greater arterial stiffness and endothelial dysfunction compared to European Caucasians, largely driven by underlying glycemic status.
Gunarathne et al. (2009) conducted a cross-sectional in Stroke (n=293). South Asian ethnicity and glycemic status vs. European Caucasian ethnicity and healthy controls was evaluated on Arterial stiffness and endothelial-dependent vascular function (p=<0.001). South Asian stroke survivors had higher arterial stiffness and impaired endothelial function compared to European Caucasians (P<0.001), abnormalities independently associated with glycemic status.