Key points are not available for this paper at this time.
Low-pH inhibition links coxsackievirus B3 elution and eclipse in HeLa cells; leaves open relevance to cardiac infection models.
Purified coxsackievirus B3 labeled with 32P- or 14C-valine interacted with HeLa cells in a manner resembling that found by others for poliovirus. Radioactivity eluted from cells at 37°, pH 7, as noninfectious virus, but contained infectious RNA. Both elution and “eclipse” of virus were inhibited irreversibly at low pH to provide further evidence that these processes may be related properties of the cell surface.
No takes yet. Share an insight, caveat, or question.
Crowell et al. (1971) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: