This study was designed to determine whether cumulus oophorus cells secrete progesterone. Immature PMS‐primed, hCG‐treated rats were used. Their cumuli were isolated from pre‐ovulatory (no hCG) and peri‐ovulatory (after hCG) follicles, and from post‐ovulatory oviducal ampullae. Treatment with hCG increased progesterone secretion by almost two‐and‐one‐half‐fold. It was speculated that the cumulus oophorus secretion of progesterone modifies the accumulation of fluid in the ampulla, thus providing the medium in which fertilization takes place.
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Sherizly et al. (1980) studied this question.
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