Key result
Etomidate provided more stable hemodynamic conditions during induction of general anesthesia compared to propofol, which caused significant reductions in heart rate and blood pressure.
Why the study?
The study was conducted to compare hemodynamic changes occurring due to propofol and etomidate as induction agents during general anesthesia at a tertiary care centre.
Does etomidate improve hemodynamic stability compared to propofol as an induction agent in adult patients undergoing elective surgeries?
Does etomidate improve hemodynamic stability compared to propofol as an induction agent in adult patients undergoing elective surgeries?
Etomidate provides better hemodynamic stability than propofol when used as an induction agent for general anesthesia in ASA 1 and 2 patients.
May favor etomidate for induction stability in low-risk patients; leaves open confirmation by randomized trials.
Aims: To compare hemodynamic changes occurring due to Propofol and Etomidate during general anesthesia as induction agents at a Tertiary Care Centre. Materials and Methods: 68 Adult ASA1 and ASA 2 Patients undergoing elective surgeries under gender anaesthesia in the department of Anaesthesia, Medical college and tertiary health care Centre after considering and satisfying the inclusion and exclusion criteria were selected and divided in two equal groups. They were given Propofol (2mg/kg) and Etomidate (0.3mg/kg) and hemodynamics were compared. Results: Etomidate was having more stable hemodynamic conditions as compared to Propofol induced anaesthesia. There was significant reduction in heart rate and blood pressure leading to hypotension in propofol group while etomidate group had stable hemodynamics. Conclusion: This study concludes that etomidate is a better agent for induction than propofol in view of hemodynamic stability.
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Koshire et al. (2021) studied Patients undergoing elective surgeries under general anaesthesia (n=68). Etomidate vs. Propofol (2mg/kg) was evaluated on Hemodynamic changes. Etomidate provided more stable hemodynamic conditions during induction of general anesthesia compared to propofol, which caused significant reductions in heart rate and blood pressure.
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