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Natural and X-ray induced mutations rendered strains of Streptomyces scabies simultaneously tyrosinase-deficient and unable to form a "brown-ring" in skim milk. These results and the presence of the tyrosinase reaction in each of 80 brown-ring positive streptomycetes tested were considered to indicate the identity of the brown-ring test and the tyrosinase reaction. All 12 tyrosinase-deficient mutants tested were virulent for Katahdin potatoes in controlled greenhouse tests.
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Gregory et al. (1956) studied this question.
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