Key result
Older adults with type 2 diabetes maintained baseline cognitive deficits and developed new deficits in reaction time over 3 years, though no differential short-term change was observed.
Why the study?
Does type 2 diabetes affect longitudinal cognitive performance in older adults?
Cohort (n=300)
Does type 2 diabetes affect longitudinal cognitive performance in older adults?
Type 2 diabetes in older adults is associated with both persistent and newly developing cognitive deficits over a short-term 3-year period.
Diabetes-associated cognitive deficits support monitoring in older adults; extends cross-sectional data but leaves causal effects and interventions open.
Type 2 diabetes is associated with cognitive deficits, although inconsistently across neuropsychological domains. We examined 3-year longitudinal data from the Victoria Longitudinal Study, comparing diabetes (n = 28) and control (n = 272) older adults on a comprehensive neuropsychological battery. Assessing potential change and stability, we found that (a) baseline diabetes group deficits in semantic speed and speed-intensive executive function were preserved, (b) new average deficits for reaction time and nonspeeded executive function appeared, and (c) no differential short-term change was observed. It is clinically and theoretically important to examine sequential change in multiple domains over time.
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Fischer et al. (2009) conducted a cohort in Type 2 diabetes (n=300). Type 2 diabetes vs. Control was evaluated on Cognitive performance on a comprehensive neuropsychological battery. Older adults with type 2 diabetes maintained baseline cognitive deficits and developed new deficits in reaction time over 3 years, though no differential short-term change was observed.
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