You oughta use water: Broad functional-group (FG) tolerance was observed for the title coupling of aryl halides (X = Cl, Br, I) and aryl boronic acids to give biaryl compounds with up to 94% ee. The chiral imidazoindole phosphine-palladium catalyst supported on an amphiphilic polystyrene-poly(ethylene glycol) (PS-PEG) resin could be recycled readily.
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Uozumi et al. (2009) studied this question.
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