Asymmetric Synthesis of Biaryls by Intramolecular Oxidative Couplings of Cyanocuprate Intermediates

This is the authors' abstract. We don't add key points for this paper.

With a judicious choice of tether from the “chiral pool”, coupling of the two aryl rings in nonracemic 1 yields only one of the two possible diastereomers of biaryl 2. G  C or O substituent; R, R′  H, 3OMe. This method is expected to be widely applicable.