Key result
Levosimendan improved symptomatology and cardiac function in a pregnant patient with methamphetamine-induced dilated cardiomyopathy, enabling a safe cesarean delivery.
Why the study?
Does levosimendan improve symptoms and cardiac function in a pregnant patient with methamphetamine-induced dilated cardiomyopathy?
Case Report (n=1)
Does levosimendan improve symptoms and cardiac function in a pregnant patient with methamphetamine-induced dilated cardiomyopathy?
Levosimendan can be safely and effectively used to stabilize pregnant patients with severe dilated cardiomyopathy secondary to methamphetamine use prior to cesarean delivery.
May facilitate delivery in methamphetamine-associated peripartum cardiomyopathy; hypothesis-generating and should not change practice.
Background: Dilated Cardiomyopathy (DCM) is characterized by dilation of the left ventricle (LV) and, by consequence contractile dysfunction. DCM is caused by multiple etiologies, often the result of myocarditis, alcohol consumption, drugs and metabolic or endocrine alterations. Case: We report the case of a 36-year-old patient with a 27.6-week pregnancy with a pathological history of Heart Failure (HF) of 4 years, alcoholism of more than 15 years, methamphetamine use of more than 3 years. She presented agitation and class III dyspnea, the fatigue progressed until she presented respiratory distress accompanied by edema of the lower limbs, an echocardiogram was performed, Dilated Cardiomyopathy was diagnosed and therefore primary management was made with levosimendan and diuretic then cesarean surgery was performed. Conclusion: for this patient the use of levosimendan was beneficial, improving the symptomatology, increasing the cardiac function and making possible the performance of the cesarean delivery. There was no harm for the patient or the baby.
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Carlos Pablo Guerrero-Del Bosque MD (2022) conducted a case report in Dilated Cardiomyopathy (n=1). Levosimendan was evaluated on Clinical improvement and successful delivery. Levosimendan improved symptomatology and cardiac function in a pregnant patient with methamphetamine-induced dilated cardiomyopathy, enabling a safe cesarean delivery.
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