Cladribine improves lung cysts and pulmonary function in a child with histiocytosis

Langerhans’ cell histiocytosis (LCH) is a rare disease of unknown aetiology involving accumulation of Langerhans’ cells organised in granuloma, in various organs [1]. Pulmonary LCH (PLCH) is characterised by focal Langerhans’ cell granulomas infiltrating and destroying distal bronchioles, which results in cysts, major destruction of the pulmonary tissue and pneumothorax [2, 3]. PLCH is rare in children <18 years old. Cladribine treatment has marked efficacy for clinical, functional and imaging outcomes in a child with PCLH <http://ow.ly/CK3XJ> The authors thank the patient and the family for their participation. The authors thank Abdellatif Tazi (Service de pneumologie, Hôpital Saint-Louis, Paris, France) for council.