Cellobiohydrolase from Trichoderma reesei.

The secondary structure pattern of a cellobiohydrolase from Trichoderma reesei was predicted using three different algorithms. The relative amounts of the different secondary structure classes derived by this procedure were in good agreement with the values determined by circular dichroism measurements. A twofold internal sequence homology with a repeat distance of approximately 200 residues is observed and possibly also a third, partial, repetition in the C ‐terminal region. The predicted secondary structure and hydrophobicity pattern show a similar repeat.