Key result
The 2013 ACC/AHA pooled cohort equations predicted an average 10-year ASCVD risk of 12.5% among Chinese adults, overclassifying 29.0% of individuals compared to the Chinese model.
Why the study?
Does the 2013 ACC/AHA pooled cohort equation model differ from the Chinese ICVD model in estimating 10-year cardiovascular risk among Chinese adults?
Cross-Sectional (n=61,541)
Yes
Does the 2013 ACC/AHA pooled cohort equation model differ from the Chinese ICVD model in estimating 10-year cardiovascular risk among Chinese adults?
The 2013 ACC/AHA pooled cohort equations predict a higher 10-year ASCVD risk compared to the Chinese ICVD model, potentially overclassifying risk in Chinese adults.
OBJECTIVE: To establish the distribution of 10-year atherosclerotic cardiovascular disease (ASCVD) risk among Chinese adults. METHODS: We estimated the 10-year ASCVD risk by applying the 2013 American College of Cardiology/ American Heart Association pooled cohort equations (PCEs) to the data obtained from the 2010 China Chronic Disease and Risk Factor Surveillance that involved 61,541 participants (representing 520,158,652 Chinese adults) aged 40-79 years. We also compared the ASCVD risk with the 10-year ischemic cardiovascular disease (ICVD) risk, which was calculated using the simplified scoring tables recommended by the Chinese Guidelines for Prevention of Cardiovascular Diseases (Chinese model). RESULTS: Based on the PCEs, the average 10-year ASCVD risk among adults without self-reported stroke or myocardial infraction was 12.5%. Approximately 247 million (47.4%) and 107 million (20.6%) adults had ⋝ 7.5% and > 20% 10-year ASCVD risks, respectively. The 10-year ASCVD risk > 20% was higher among men, less educated individuals, smokers, drinkers, and physically inactive individuals than among their counterparts. Overall, 29.0% of adults categorized using the Chinese model were overclassified with the PCEs. CONCLUSION: Our results define the distribution of 10-year ASCVD risk among Chinese adults. The 10-year ASCVD risk predicted by the PCEs was higher than the ICVD risk predicted by the Chinese model.
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Zhang et al. (2017) conducted a cross-sectional in Atherosclerotic cardiovascular disease (n=61,541). 2013 ACC/AHA pooled cohort equations (PCEs) vs. Chinese Guidelines for Prevention of Cardiovascular Diseases (Chinese model) was evaluated on 10-year ASCVD risk. The 2013 ACC/AHA pooled cohort equations predicted an average 10-year ASCVD risk of 12.5% among Chinese adults, overclassifying 29.0% of individuals compared to the Chinese model.
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