February 1, 1928Journal of Clinical InvestigationOpen Access

Circulatory Adjustment in Anemia

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Population

8 anemic subjects with initial oxygen capacities of 5.4 to 14.4 volumes per cent.

Design

Case_series

Authors

DRDickinson W. RichardsJohannesburg Hospital MSMarjorie L. StraussPresbyterian Hospital

Discussion

Member takes

Implication

The circulatory adjustment to anemia involves both an increase in cardiac output and an increased percentage utilization of oxygen by the tissues.

Structured PICO

Population

8 anemic subjects (2 primary anemia, 4 secondary anemia following hemorrhage from gastric or duodenal ulcer, 1 secondary anemia with carcinoma of the stomach, 1 secondary anemia associated with purpuric manifestations) with initial oxygen capacities of 5.4 to 14.4 volumes per cent.

Outcome

Cardiac output per minute and other circulatory functions (oxygen utilization, metabolic rate, respiratory quotient, ApH)surrogate

The circulatory adjustment to anemia involves both an increase in cardiac output and an increased percentage utilization of oxygen by the tissues.

Limitations

Difficulty obtaining accurate alveolar air measurements in untrained subjects
Blood pressure measurements were not made

Cite This Study

Richards et al. (1928) studied this question.

synapsesocial.com/papers/6a849772cdf3a848bdbd9650 https://doi.org/10.1172/jci100151

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Implication

The circulatory adjustment to anemia involves both an increase in cardiac output and an increased percentage utilization of oxygen by the tissues.

Circulatory Adjustment in Anemia

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Circulatory Adjustment in Anemia

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider