Why the study?
While other single-shot devices have limited ability to accommodate pulmonary vein anatomical variations, it is unknown whether pulsed-field ablation is suited for variants such as a left common pulmonary vein.
Does pulsed-field ablation for pulmonary vein isolation provide safe and effective clinical outcomes in patients with atrial fibrillation and a left common pulmonary vein?
Does pulsed-field ablation for pulmonary vein isolation provide safe and effective clinical outcomes in patients with atrial fibrillation and a left common pulmonary vein?
This study evaluates the feasibility, safety, and clinical outcomes of using pulsed-field ablation for pulmonary vein isolation in patients with the anatomic variation of a left common pulmonary vein.
Supports PFA-PVI feasibility in left common PV; hypothesis-generating and requires randomized confirmation before practice change.
Pulmonary vein isolation (PVI) by pulsed-field ablation (PFA) has demonstrated encouraging clinical results for the treatment of atrial fibrillation (AF).1,2 Whereas the ability of other single-shot devices, such as cryoballoon-ablation systems, to accommodate for anatomic variations of the pulmonary veins (PVs) is limited,3–5 it is currently unknown if PFA is suited for PV variants such as a left common pulmonary vein (LCPV). This study aims to assess procedural characteristics, safety, and clinical outcomes of PFA-based PVI in patients with LCPVs.
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Jordan et al. (2024) studied this question.
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