Why the study?
Does serum Cystatin C predict the presence of coronary artery disease in patients with type 2 diabetes?
Does serum Cystatin C predict the presence of coronary artery disease in patients with type 2 diabetes?
Serum Cystatin C levels are significantly altered in type 2 diabetes patients and show moderate diagnostic accuracy for predicting the presence of coronary artery disease.
Cystatin C shows moderate CAD accuracy in T2DM; hypothesis-generating and requires prospective validation before any clinical use.
The association between Coronary Artery Disease (CAD) and diabetes is strong and has led to screening strategies in diabetic patients even before they are symptomatic. Diabetic patients often are unaware of myocardial ischemic pain, and so silent myocardial infarction and ischemia are markedly increased in this population. There is a high chance of developing sudden cardiac death in those with diabetes.
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Bablu Sukla Das (2013) studied this question.
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