Gold(I) iodide catalyzed Sonogashira reactions have been developed. Terminal alkynes reacted with aryl iodides and bromides smoothly in the presence of AuI (1 mol‐%) and dppf (1 mol‐%) in toluene to generate the corresponding cross‐coupling products in good to excellent yields. Furthermore, aromatic terminal alkynes could also react with 2‐iodoaniline to form substituted indoles in excellent yields through a coupling–cyclization reaction sequence under the present reaction conditions.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
No takes yet. Share an insight, caveat, or question.
Li et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: