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Phosphate monoester of tetra(butylene 1,4-glycol) monobutyl ether was combined with dioctadecyldimetylammonium cation to make an ion pair. When inserted into planar lipid bilayers, it afforded stable and constant single ion channel currents. The open probabilities varied depending on the applied voltage while keeping the conductance constant, giving rise to a mimic of the voltage dependence.
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Kobuke et al. (1995) studied this question.
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