Radiological study of skeletal metastases from cerebellar medulloblastoma

Skeletal metastases from cerebellar medulloblastoma are extremely rare. When they occur, they produce widespread areas of bone destruction and new bone formation. Either process may predominate over the other. Occasionally the lesion is solitary. Periosteal reaction may occur and the new bone is usually perpendicular to the shaft. The sites most commonly involved are the axial skeleton, the pelvic and shoulder girdles and adjacent ends of long bones, the ribs and the skull. In the long bones, the lesions are usually metaphyseal, but they may also involve the epiphyses. The influence of cytotoxic drugs on the radiological appearances is described.