Why the study?
Does L-dopa improve clinical assessments in patients with chronic schizophrenia?
Population
28 patients with chronic schizophrenia
Comparison
L-dopa added to regular neuroleptic medication vs Placebo added to regular neuroleptic medication
Design
RCT, double blind
Follow-up
6 weeks
Authors
Loading...
Mixed ratings across assessors advise against L-dopa for chronic schizophrenia; leaves open adjunctive efficacy for larger trials.
Does L-dopa improve clinical assessments in patients with chronic schizophrenia?
In a small trial of chronic schizophrenia patients, L-dopa added to neuroleptics yielded mixed results, with significant improvement noted only in nurse ratings.
BUCHANAN et al. (1975) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: