Summary Plasma oestriol was measured serially in a group of patients considered to have intrauterine fetal growth retardation. The levels in the four patients who developed hypertension and gave birth to infants of low birthweight were all less than the normal average whilst seven of the nine normotensive patients with low birthweight infants had a different form of abnormal curve. Those who had infants of normal birthweight had normal values.
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Gordon M. Masson (1973) studied this question.
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