Right ventricular peak systolic longitudinal strain is a sensitive marker for right ventricular deterioration in adult patients with tetralogy of Fallot
Why the study?
Does right ventricular longitudinal peak systolic strain detect early right ventricular deterioration better than ejection fraction in adult patients with corrected tetralogy of Fallot?
Population
18 adult patients with corrected tetralogy of Fallot (TOF) and healthy controls
Comparison
Echocardiographic speckle-tracking… vs Healthy controls and baseline values
Design
Cohort
Follow-up
4.2 +/- 1.7 years
Authors
Discussion
Loading...
Member takes
Implication
May enable earlier RV dysfunction detection than EF in repaired TOF; hypothesis-generating and needs prospective validation before practice change.
Structured PICO
Does right ventricular longitudinal peak systolic strain detect early right ventricular deterioration better than ejection fraction in adult patients with corrected tetralogy of Fallot?
P
Population
18 adult patients with corrected tetralogy of Fallot (TOF) and healthy controls
I
Intervention
Echocardiographic speckle-tracking strain-analysis for right ventricular longitudinal peak systolic strain (LPSS) and Cardiac Magnetic Resonance (CMR)
C
Comparator
Healthy controls (for baseline comparison) and baseline values (for longitudinal follow-up)
O
Outcome
Changes in right ventricular global longitudinal peak systolic strain (GLPSS), free wall LPSS, and CMR-derived RV ejection fraction over timesurrogate
Right ventricular longitudinal peak systolic strain is a sensitive marker that detects early right ventricular deterioration before changes in ejection fraction occur in adults with corrected tetralogy of Fallot.
Cite This Study
Scherptong et al. (2009) studied this question.