Why the study?
Women with PCOS have an increased risk of cardiovascular disease, making the detection of impaired left ventricular function important in managing this condition.
Are there variations in echocardiographic measures of left ventricular function between women with PCOS and healthy controls?
Are there variations in echocardiographic measures of left ventricular function between women with PCOS and healthy controls?
Women with PCOS exhibit significant differences in echocardiographic measures of left ventricular diastolic function compared to healthy controls, suggesting early preclinical cardiovascular changes.
May prompt earlier echocardiographic screening in PCOS; confirms preclinical LV impairment but leaves causal impact on outcomes open.
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of childbearing age, causing hormonal imbalances, reproductive issues, and metabolic disturbances. Women with PCOS have an increased risk of cardiovascular disease due to insulin resistance, obesity, and hyperandrogenism. Detecting impaired left ventricular (LV) function is important in managing this condition. Echocardiography, a non-invasive imaging technique, can effectively detect LV dysfunction. Aim: The goal of this systematic review was to assess whether there are any variations in echocardiographic measures between women with PCOS and those without the condition in order to determine the potential impact of PCOS on LV function. Methods: This review followed the PRISMA reporting guidelines. A thorough search of databases including PubMed, Scopus, Web of Science, and Cochrane was conducted. The quality of the selected studies was assessed using the Joanna Briggs Institute appraisal instruments. After applying strict eligibility criteria, data were extracted and organized in Microsoft Excel sheets. Review Manager (RevMan) software was used for the analysis. Results: Analysis of 29 studies revealed significant differences in echocardiographic measures related to diastolic function between women with PCOS and healthy controls. However, there were no significant differences in measures of systolic function. Conclusion: These findings indicate that PCOS may be linked to impaired LV function, thereby increasing the risk of cardiovascular disease. Further research is necessary to better understand this association and its clinical implications. Early detection and management of PCOS could potentially help prevent cardiovascular complications in affected women.
No takes yet. Share an insight, caveat, or question.
Mirzohreh et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: