The right hemithorax of rats was exposed to 3 kR of X rays; the animals were sacrificed at different times after exposure up to 9 months, and various biochemical parameters were determined. After a slight early decrease, collagen increased during the fibrotic stage. An increase during fibrosis was also seen for DNA, ..beta..-glucuronidase, cathepsin, histamine, serotonin, and lipid peroxides. Fibrinolytic activity was found to be depressed at most time points studied.
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Dancewicz et al. (1976) studied this question.
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