Ulcerative Hodgkin's Disease and Lymph Node Imprints

Cases of Hodgkin's disease with cutaneous manifestations have previously been studied with the usual fixation technic of the skin and node tissue. We wish to report the great value of node and skin imprints in the study of this disease. The frequency of cutaneous involvement has been given by different authors as varying from 16 per cent (by Barron1) and 29 per cent (by Wallhauser2) to 38 per cent (by Goldman3and Cole4). Miller5has mentioned that these manifestations are of two types, the nonspecific and the specific. The nonspecific manifestations, lacking the characteristic histopathologic changes, include diverse conditions ranging from generalized pruritus, lichenification, urticaria, prurigolike nodules, bullous eruptions, exfoliative erythrodermas and pigmentation to loss of hair and changes in the nails. They have also been labeled as ids or lymphogranulids by Nanta and Chatellier.6The specific lesions, those hav