Cancer chemotherapy is usually necessary and to date remains the best way to reduce the size of solid tumors, eliminate tumor residues and prevent tumor metastasis after surgery. However, anti-cancer drugs such as Taxol and cisplatinum-based drugs frequently suffer from low water solubility and result in adverse side effects. An injectable delivery system that can sustainedly release anti-cancer drugs may improve the efficiency of chemotherapy and prolong the life of patients. We highlight in this paper on a novel self-delivery system of molecular hydrogels based on anti-cancer drugs. This novel kind of self-delivery system with a high weight percentage of anti-cancer drugs is injectable and can release anti-cancer drugs sustainedly over a long period of time. It might be administrated to the inside of tumors to reduce the their size for patients in a late stage of cancer or administrated in the cavities left by tumor removal to eliminate tumor residues and prevent metastasis.
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Wang et al. (2011) studied this question.
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